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Fecal microbiota transplantation from young mice rejuvenates aged hematopoietic stem cells by suppressing inflammation

Hematopoietic stem cell (HSC) aging is accompanied by hematopoietic reconstitution dysfunction, including loss of regenerative and engraftment ability, myeloid differentiation bias, and elevated risks of hematopoietic malignancies. Gut microbiota, a key regulator of host health and immunity, has rec...

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Detalles Bibliográficos
Autores principales: Zeng, Xiangjun, Li, Xiaoqing, Li, Xia, Wei, Cong, Shi, Ce, Hu, Kejia, Kong, Delin, Luo, Qian, Xu, Yulin, Shan, Wei, Zhang, Meng, Shi, Jimin, Feng, Jingjing, Han, Yingli, Huang, He, Qian, Pengxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646769/
https://www.ncbi.nlm.nih.gov/pubmed/36638348
http://dx.doi.org/10.1182/blood.2022017514