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SBNO2 is a critical mediator of STAT3-driven hematological malignancies

Gain-of-function mutations in the signal transducer and activator of transcription 3 (STAT3) gene are recurrently identified in patients with large granular lymphocytic leukemia (LGLL) and in some cases of natural killer (NK)/T-cell and adult T-cell leukemia/lymphoma. To understand the consequences...

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Detalles Bibliográficos
Autores principales: Brandstoetter, Tania, Schmoellerl, Johannes, Grausenburger, Reinhard, Kollmann, Sebastian, Doma, Eszter, Huuhtanen, Jani, Klampfl, Thorsten, Eder, Thomas, Grebien, Florian, Hoermann, Gregor, Zuber, Johannes, Mustjoki, Satu, Maurer, Barbara, Sexl, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646773/
https://www.ncbi.nlm.nih.gov/pubmed/36630607
http://dx.doi.org/10.1182/blood.2022018494