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Duodenal macrophages control dietary iron absorption via local degradation of transferrin

Iron is an essential cellular metal that is important for many physiological functions including erythropoiesis and host defense. It is absorbed from the diet in the duodenum and loaded onto transferrin (Tf), the main iron transport protein. Inefficient dietary iron uptake promotes many diseases, bu...

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Detalles Bibliográficos
Autores principales: Sukhbaatar, Nyamdelger, Schöller, Maria, Fritsch, Stephanie Deborah, Linke, Monika, Horer, Stefanie, Träger, Manuela, Mazić, Mario, Forisch, Stephan, Gonzales, Karine, Kahler, Jan Pascal, Binder, Carina, Lassnig, Caroline, Strobl, Birgit, Müller, Mathias, Scheiber-Mojdehkar, Barbara, Gundacker, Claudia, Dabsch, Stefanie, Kain, Renate, Hengstschläger, Markus, Verhelst, Steven H. L., Weiss, Günter, Theurl, Igor, Weichhart, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646810/
https://www.ncbi.nlm.nih.gov/pubmed/37018657
http://dx.doi.org/10.1182/blood.2022016632