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Iron homeostasis governs erythroid phenotype in polycythemia vera

Polycythemia vera (PV) is a myeloproliferative neoplasm driven by activating mutations in JAK2 that result in unrestrained erythrocyte production, increasing patients’ hematocrit and hemoglobin concentrations, placing them at risk of life-threatening thrombotic events. Our genome-wide association st...

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Detalles Bibliográficos
Autores principales: Bennett, Cavan, Jackson, Victoria E., Pettikiriarachchi, Anne, Hayman, Thomas, Schaeper, Ute, Moir-Meyer, Gemma, Fielding, Katherine, Ataide, Ricardo, Clucas, Danielle, Baldi, Andrew, Garnham, Alexandra L., Li-Wai-Suen, Connie S. N., Loughran, Stephen J., Baxter, E. Joanna, Green, Anthony R., Alexander, Warren S., Bahlo, Melanie, Burbury, Kate, Ng, Ashley P., Pasricha, Sant-Rayn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646816/
https://www.ncbi.nlm.nih.gov/pubmed/36928379
http://dx.doi.org/10.1182/blood.2022016779