TREM2 acts as a receptor for IL-34 to suppress acute myeloid leukemia in mice

The bone marrow microenvironment supports leukocyte mobilization and differentiation and controls the development of leukemias, including acute myeloid leukemia (AML). Here, we found that the development of AML xenotransplants was suppressed in mice with osteoclasts tuberous sclerosis 1 (Tsc1) delet...

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Detalles Bibliográficos
Autores principales: Xie, Xiaoling, Zhang, Wuju, Xiao, Min, Wei, Tiantian, Qiu, Yingqi, Qiu, Jingyang, Wang, Hao, Qiu, Zeyou, Zhang, Sheng, Pan, Yating, Mao, Linlin, Li, Yuhua, Guo, Bin, Yang, Wanwen, Hu, Yuxing, Hu, Shujie, Gong, Yan, Yang, Jun, Xiao, Guozhi, Zhang, Yue, Bai, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Myeloid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646818/
https://www.ncbi.nlm.nih.gov/pubmed/37001042
http://dx.doi.org/10.1182/blood.2022018619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646818/
https://www.ncbi.nlm.nih.gov/pubmed/37001042
http://dx.doi.org/10.1182/blood.2022018619

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