Nickel-catalysed asymmetric hydromonofluoromethylation of 1,3-enynes for enantioselective construction of monofluoromethyl-tethered chiral allenes

An unprecedented nickel-catalysed enantioselective hydromonofluoromethylation of 1,3-enynes is developed, allowing the diverse access to monofluoromethyl-tethered axially chiral allenes, including the challenging deuterated monofluoromethyl (CD(2)F)-tethered ones that are otherwise inaccessible. It...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Yang, Jimin, Ruan, Yu-Long, Liao, Ling, Ma, Chuang, Xue, Xiao-Song, Yu, Jin-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646904/
https://www.ncbi.nlm.nih.gov/pubmed/38020394
http://dx.doi.org/10.1039/d3sc04474b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646904/
https://www.ncbi.nlm.nih.gov/pubmed/38020394
http://dx.doi.org/10.1039/d3sc04474b

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