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Nickel-catalysed asymmetric hydromonofluoromethylation of 1,3-enynes for enantioselective construction of monofluoromethyl-tethered chiral allenes

An unprecedented nickel-catalysed enantioselective hydromonofluoromethylation of 1,3-enynes is developed, allowing the diverse access to monofluoromethyl-tethered axially chiral allenes, including the challenging deuterated monofluoromethyl (CD(2)F)-tethered ones that are otherwise inaccessible. It...

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Detalles Bibliográficos
Autores principales:	Zhang, Ying, Yang, Jimin, Ruan, Yu-Long, Liao, Ling, Ma, Chuang, Xue, Xiao-Song, Yu, Jin-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646904/ https://www.ncbi.nlm.nih.gov/pubmed/38020394 http://dx.doi.org/10.1039/d3sc04474b

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