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Disease activity drives transcriptomic heterogeneity in early untreated rheumatoid synovitis

OBJECTIVES: Transcriptomic profiling of synovial tissue from patients with early, untreated rheumatoid arthritis (RA) was used to explore the ability of unbiased, data-driven approaches to define clinically relevant subgroups. METHODS: RNASeq was performed on 74 samples, with disease activity data c...

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Detalles Bibliográficos
Autores principales: Triaille, Clément, Tilman, Gaëlle, Sokolova, Tatiana, Loriot, Axelle, Marchandise, Joelle, De Montjoye, Stéphanie, Nzeusseu-Toukap, Adrien, Méric de Bellefon, Laurent, Bouzin, Caroline, Galant, Christine, Durez, Patrick, Lauwerys, Bernard R, Limaye, Nisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646909/
https://www.ncbi.nlm.nih.gov/pubmed/37507201
http://dx.doi.org/10.1136/ard-2023-224068