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Discovery of reactive peptide inhibitors of human papillomavirus oncoprotein E6

Human papillomavirus (HPV) infections account for nearly all cervical cancer cases, which is the fourth most common cancer in women worldwide. High-risk variants, including HPV16, drive tumorigenesis in part by promoting the degradation of the tumor suppressor p53. This degradation is mediated by th...

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Detalles Bibliográficos
Autores principales: Ye, Xiyun, Zhang, Peiyuan, Tao, Jason, Wang, John C. K., Mafi, Amirhossein, Grob, Nathalie M., Quartararo, Anthony J., Baddock, Hannah T., Chan, Leanne J. G., McAllister, Fiona E., Foe, Ian, Loas, Andrei, Eaton, Dan L., Hao, Qi, Nile, Aaron H., Pentelute, Bradley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646941/
https://www.ncbi.nlm.nih.gov/pubmed/38020382
http://dx.doi.org/10.1039/d3sc02782a