Enzyme-Responsive Nanoparticles for the Targeted Delivery of an MMP Inhibitor to Acute Myocardial Infarction

[Image: see text] Herein, we have developed a drug-loaded matrix metalloproteinase (MMP)-responsive micellar nanoparticle (NP) intended for minimally invasive intravenous injection during the acute phase of myocardial infarction (MI) and prolonged retention in the heart for small-molecule drug deliv...

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Detalles Bibliográficos
Autores principales: Sullivan, Holly L., Liang, Yifei, Worthington, Kendra, Luo, Colin, Gianneschi, Nathan C., Christman, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646957/
https://www.ncbi.nlm.nih.gov/pubmed/37695847
http://dx.doi.org/10.1021/acs.biomac.3c00421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646957/
https://www.ncbi.nlm.nih.gov/pubmed/37695847
http://dx.doi.org/10.1021/acs.biomac.3c00421

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