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Membrane-Active Thermoresponsive Block Copolymers Containing a Diacylglycerol-Based Segment: RAFT Synthesis, Doxorubicin Encapsulation, and Evaluation of Cytotoxicity against Breast Cancer Cells

[Image: see text] Herein, we report the formation of drug delivery systems from original thermoresponsive block copolymers containing lipid-based segments. Two acrylate monomers derived from palmitic- or oleic-acid–based diacylglycerols (DAGs) were synthesized and polymerized by the reversible addit...

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Detalles Bibliográficos
Autores principales: Kurowska, Izabela, Markiewicz, Karolina H., Niemirowicz-Laskowska, Katarzyna, Destarac, Mathias, Wielgat, Przemysław, Misztalewska-Turkowicz, Iwona, Misiak, Paweł, Car, Halina, Wilczewska, Agnieszka Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646981/
https://www.ncbi.nlm.nih.gov/pubmed/37842917
http://dx.doi.org/10.1021/acs.biomac.3c00580