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Proteomics and mathematical modeling of longitudinal CSF differentiates fast versus slow ALS progression

OBJECTIVE: Amyotrophic lateral sclerosis (ALS) is a heterogeneous disease with a complex etiology that lacks biomarkers predicting disease progression. The objective of this study was to use longitudinal cerebrospinal fluid (CSF) samples to identify biomarkers that distinguish fast progression (FP)...

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Detalles Bibliográficos
Autores principales: Vu, Lucas, Garcia‐Mansfield, Krystine, Pompeiano, Antonio, An, Jiyan, David‐Dirgo, Victoria, Sharma, Ritin, Venugopal, Vinisha, Halait, Harkeerat, Marcucci, Guido, Kuo, Ya‐Huei, Uechi, Lisa, Rockne, Russell C., Pirrotte, Patrick, Bowser, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647001/
https://www.ncbi.nlm.nih.gov/pubmed/37646115
http://dx.doi.org/10.1002/acn3.51890