Intranasal neuropeptide Y1 receptor antagonism improves motor deficits in symptomatic SOD1 ALS mice

OBJECTIVE: Neuropeptide Y (NPY) is a 36 amino acid peptide widely considered to provide neuroprotection in a range of neurodegenerative diseases. In the fatal motor neuron disease amyotrophic lateral sclerosis (ALS), recent evidence supports a link between NPY and ALS disease processes. The goal of...

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Detalles Bibliográficos
Autores principales: Clark, Rosemary M., Clark, Courtney M., Lewis, Katherine E.A., Dyer, Marcus S., Chuckowree, Jyoti A., Hoyle, Joshua A., Blizzard, Catherine A., Dickson, Tracey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647012/
https://www.ncbi.nlm.nih.gov/pubmed/37644692
http://dx.doi.org/10.1002/acn3.51885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647012/
https://www.ncbi.nlm.nih.gov/pubmed/37644692
http://dx.doi.org/10.1002/acn3.51885

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