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Optimizing the balance between heterologous acetate- and CO(2)-reduction pathways in anaerobic cultures of Saccharomyces cerevisiae strains engineered for low-glycerol production
In anaerobic Saccharomyces cerevisiae cultures, NADH (reduced form of nicotinamide adenine dinucleotide)-cofactor balancing by glycerol formation constrains ethanol yields. Introduction of an acetate-to-ethanol reduction pathway based on heterologous acetylating acetaldehyde dehydrogenase (A-ALD) ca...
Autores principales: | van Aalst, Aafke C A, Geraats, Ellen H, Jansen, Mickel L A, Mans, Robert, Pronk, Jack T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647013/ https://www.ncbi.nlm.nih.gov/pubmed/37942589 http://dx.doi.org/10.1093/femsyr/foad048 |
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