Proto-oncogene mutations in middle ear cholesteatoma contribute to its pathogenesis

BACKGROUND: Chronic inflammation causes bone destruction in middle ear cholesteatomas (MECs). However, the causes of their neoplastic features remain unknown. The present study demonstrated for the first time that neoplastic features of MEC are based on proto-oncogene mutations. RESULTS: DNA was ext...

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Detalles Bibliográficos
Autores principales: Satoh, Chisei, Yoshiura, Koh-ichiro, Mishima, Hiroyuki, Yoshida, Haruo, Takahashi, Haruo, Kumai, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647096/
https://www.ncbi.nlm.nih.gov/pubmed/37968650
http://dx.doi.org/10.1186/s12920-023-01640-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647096/
https://www.ncbi.nlm.nih.gov/pubmed/37968650
http://dx.doi.org/10.1186/s12920-023-01640-6

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