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Proto-oncogene mutations in middle ear cholesteatoma contribute to its pathogenesis
BACKGROUND: Chronic inflammation causes bone destruction in middle ear cholesteatomas (MECs). However, the causes of their neoplastic features remain unknown. The present study demonstrated for the first time that neoplastic features of MEC are based on proto-oncogene mutations. RESULTS: DNA was ext...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647096/ https://www.ncbi.nlm.nih.gov/pubmed/37968650 http://dx.doi.org/10.1186/s12920-023-01640-6 |