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Monoclonal enolase-1 blocking antibody ameliorates pulmonary inflammation and fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a chronic fatal disease with limited therapeutic options. The infiltration of monocytes and fibroblasts into the injured lungs is implicated in IPF. Enolase-1 (ENO1) is a cytosolic glycolytic enzyme which could translocate onto the cell surface and...

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Detalles Bibliográficos
Autores principales: Huang, Wei-Ching, Chuang, Chi-Fen, Huang, Yung-Tsang, Chung, I-Che, Chen, Mao-Lin, Chuang, Tung-Yueh, Yang, Xiu-Li, Chou, Yu-Yau, Liu, Chih-Hsin, Chen, Nai-Yu, Chen, Chun-Jen, Yuan, Ta-Tung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647181/
https://www.ncbi.nlm.nih.gov/pubmed/37964270
http://dx.doi.org/10.1186/s12931-023-02583-3