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Lapatinib dysregulates HER2 signaling and impairs the viability of human uveal melanoma cells

Uveal melanoma (UM) is the principal type of intraocular malignancy in adults. Up to 50% of UM patients develop metastatic disease with very poor survival. There are few drugs available to treat the primary or metastatic UM. This study was undertaken to evaluate the anti-cancer effect of lapatinib a...

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Detalles Bibliográficos
Autores principales: Shu, Wenying, Wang, Janney Z, Zhu, Xue, Wang, Ke, Cherepanoff, Svetlana, Conway, R. Max, Madigan, Michele C, Lim, Li-Anne, Zhu, Hong, Zhu, Ling, Murray, Michael, Zhou, Fanfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647189/
https://www.ncbi.nlm.nih.gov/pubmed/38021158
http://dx.doi.org/10.7150/jca.88446