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METTL3-Dependent N6-Methyladenosine Modification Programs Human Neural Progenitor Cell Proliferation

METTL3, a methyltransferase responsible for N6−methyladenosine (m(6)A) modification, plays key regulatory roles in mammal central neural system (CNS) development. However, the specific epigenetic mechanisms governing human CNS development remain poorly elucidated. Here, we generated small−molecule−a...

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Detalles Bibliográficos
Autores principales: Zhao, Yuan, Li, Jianguo, Lian, Yilin, Zhou, Qian, Wu, Yukang, Kang, Jiuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647291/
https://www.ncbi.nlm.nih.gov/pubmed/37958523
http://dx.doi.org/10.3390/ijms242115535