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Acute Endoplasmic Reticulum Stress Suppresses Hepatic Gluconeogenesis by Stimulating MAPK Phosphatase 3 Degradation

Drug-induced liver injury (DILI) is a widespread and harmful disease, and is closely linked to acute endoplasmic reticulum (ER) stress. Previous reports have shown that acute ER stress can suppress hepatic gluconeogenesis and even leads to hypoglycemia. However, the mechanism is still unclear. MAPK...

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Detalles Bibliográficos
Autores principales: Huang, Xiaohua, Zhu, Heng, Lu, Wei, Cao, Lei, Fang, Zhengfeng, Che, Lianqiang, Lin, Yan, Xu, Shengyu, Zhuo, Yong, Hua, Lun, Jiang, Xuemei, Sun, Mengmeng, Wu, De, Feng, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647389/
https://www.ncbi.nlm.nih.gov/pubmed/37958545
http://dx.doi.org/10.3390/ijms242115561