Development of Bexarotene Analogs for Treating Cutaneous T-Cell Lymphomas

Bexarotene, a drug approved for treatment of cutaneous T-cell lymphoma (CTCL), is classified as a rexinoid by its ability to act as a retinoid X receptor (RXR) agonist with high specificity. Rexinoids are capable of inducing RXR homodimerization leading to the induction of apoptosis and inhibition o...

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Detalles Bibliográficos
Autores principales: Warda, Ankedo, Staniszewski, Lech J. P., Sabir, Zhela, Livingston, Sarah, Sausedo, Michael, Reshi, Sabeeha, Ron, Eyal, Applegate, Michael T., Haddad, Dena, Khamisi, Madleen, Marshall, Pamela A., Wagner, Carl E., Jurutka, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647404/
https://www.ncbi.nlm.nih.gov/pubmed/37947652
http://dx.doi.org/10.3390/cells12212575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647404/
https://www.ncbi.nlm.nih.gov/pubmed/37947652
http://dx.doi.org/10.3390/cells12212575

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