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Genomic Exploration of Distinct Molecular Phenotypes Steering Temozolomide Resistance Development in Patient-Derived Glioblastoma Cells

Chemotherapy using temozolomide is the standard treatment for patients with glioblastoma. Despite treatment, prognosis is still poor largely due to the emergence of temozolomide resistance. This resistance is closely linked to the widely recognized inter- and intra-tumoral heterogeneity in glioblast...

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Detalles Bibliográficos
Autores principales: Fabro, Federica, Kers, Trisha V., Feller, Kate J., Beerens, Cecile, Ntafoulis, Ioannis, Idbaih, Ahmed, Verreault, Maite, Connor, Kate, Biswas, Archita, Salvucci, Manuela, Prehn, Jochen H. M., Byrne, Annette T., O’Farrell, Alice C., Lambrechts, Diether, Dilcan, Gonca, Lodi, Francesca, Arijs, Ingrid, Kremer, Andreas, Tching Chi Yen, Romain, Chien, Miao-Ping, Lamfers, Martine L. M., Leenstra, Sieger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647455/
https://www.ncbi.nlm.nih.gov/pubmed/37958662
http://dx.doi.org/10.3390/ijms242115678