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Generation of Fibrotic Liver Organoids Using Hepatocytes, Primary Liver Sinusoidal Endothelial Cells, Hepatic Stellate Cells, and Macrophages

Liver organoids generated with single or multiple cell types have been used to investigate liver fibrosis development, toxicity, pathogenesis, and drug screening. However, organoid generation is limited by the availability of cells isolated from primary tissues or differentiated from various stem ce...

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Detalles Bibliográficos
Autores principales: Yoon, Yongdae, Gong, Seong Chan, Kim, Moon Young, Baik, Soon Koo, Hong, Ju-Eun, Rhee, Ki-Jong, Ryu, Hoon, Eom, Young Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647544/
https://www.ncbi.nlm.nih.gov/pubmed/37947592
http://dx.doi.org/10.3390/cells12212514