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Measuring Single-Cell Calcium Dynamics Using a Myofilament-Localized Optical Biosensor in hiPSC-CMs Derived from DCM Patients

Synchronized contractions of cardiomyocytes within the heart are tightly coupled to electrical stimulation known as excitation-contraction coupling. Calcium plays a key role in this process and dysregulated calcium handling can significantly impair cardiac function and lead to the development of car...

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Detalles Bibliográficos
Autores principales: Hawey, Cara, Bourque, Kyla, Alim, Karima, Derish, Ida, Rody, Elise, Khan, Kashif, Gendron, Natalie, Cecere, Renzo, Giannetti, Nadia, Hébert, Terence E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647603/
https://www.ncbi.nlm.nih.gov/pubmed/37947605
http://dx.doi.org/10.3390/cells12212526