Cargando…

Measuring Single-Cell Calcium Dynamics Using a Myofilament-Localized Optical Biosensor in hiPSC-CMs Derived from DCM Patients

Synchronized contractions of cardiomyocytes within the heart are tightly coupled to electrical stimulation known as excitation-contraction coupling. Calcium plays a key role in this process and dysregulated calcium handling can significantly impair cardiac function and lead to the development of car...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hawey, Cara, Bourque, Kyla, Alim, Karima, Derish, Ida, Rody, Elise, Khan, Kashif, Gendron, Natalie, Cecere, Renzo, Giannetti, Nadia, Hébert, Terence E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647603/ https://www.ncbi.nlm.nih.gov/pubmed/37947605 http://dx.doi.org/10.3390/cells12212526

Ejemplares similares

hiPSC-Derived Cells as Models for Drug Discovery
por: Ofir, Rivka
Publicado: (2021)

A mathematical model of hiPSC cardiomyocytes electromechanics
por: Forouzandehmehr, Mohamadamin, et al.
Publicado: (2021)

Characterizing the secretome of licensed hiPSC-derived MSCs
por: Ramos, Yolande F. M., et al.
Publicado: (2022)

Generation of hiPSC-Derived Skeletal Muscle Cells: Exploiting the Potential of Skeletal Muscle-Derived hiPSCs
por: Metzler, Eric, et al.
Publicado: (2022)

Reprogramming of HUVECs into Induced Pluripotent Stem Cells (HiPSCs), Generation and Characterization of HiPSC-Derived Neurons and Astrocytes
por: Haile, Yohannes, et al.
Publicado: (2015)

Comparison and Optimization of hiPSC Forebrain Cortical Differentiation Protocols
por: Muratore, Christina R., et al.
Publicado: (2014)

New considerations for hiPSC-based models of neuropsychiatric disorders
por: Hoffman, Gabriel E., et al.
Publicado: (2018)

The Effect of Uncoated SPIONs on hiPSC-Differentiated Endothelial Cells
por: Salingova, Barbara, et al.
Publicado: (2019)

Considerations in hiPSC-derived cartilage for articular cartilage repair
por: Yamashita, Akihiro, et al.
Publicado: (2018)

Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases
por: Trudler, Dorit, et al.
Publicado: (2021)

α-synuclein pathogenesis in hiPSC models of Parkinson’s disease
por: Baena-Montes, Jara M., et al.
Publicado: (2021)

Engineering hiPSC-CM and hiPSC-EC laden 3D nanofibrous splenic hydrogel for improving cardiac function through revascularization and remuscularization in infarcted heart
por: Guan, Ge, et al.
Publicado: (2021)

Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia
por: Brennand, K, et al.
Publicado: (2015)

Divergent Levels of Marker Chromosomes in an hiPSC-Based Model of Psychosis
por: TCW, Julia, et al.
Publicado: (2017)

Editing the genome of hiPSC with CRISPR/Cas9: disease models
por: Bassett, Andrew R.
Publicado: (2017)

Practical adoption of state-of-the-art hiPSC-cardiomyocyte differentiation techniques
por: Rupert, Cassady E., et al.
Publicado: (2020)

hiPSC-Derived Cardiac Tissue for Disease Modeling and Drug Discovery
por: Li, Junjun, et al.
Publicado: (2020)

Protocol for Tri-culture of hiPSC-Derived Neurons, Astrocytes, and Microglia
por: Ryan, Sean K., et al.
Publicado: (2020)

An in silico hiPSC-Derived Cardiomyocyte Model Built With Genetic Algorithm
por: Akwaboah, Akwasi D., et al.
Publicado: (2021)

Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids
por: Ramovs, Veronika, et al.
Publicado: (2022)

hiPSC-Derived Cells as Models for Drug Discovery 2.0
por: Ofir, Rivka
Publicado: (2023)

Vascularized hiPSC-derived 3D cardiac microtissue on chip
por: Arslan, Ulgu, et al.
Publicado: (2023)

Vascularized hiPSC-derived 3D cardiac microtissue on chip
por: Arslan, Ulgu, et al.
Publicado: (2023)

Contractile Work Contributes to Maturation of Energy Metabolism in hiPSC-Derived Cardiomyocytes
por: Ulmer, Bärbel M., et al.
Publicado: (2018)

hiPSC-Based Model of Prenatal Exposure to Cannabinoids: Effect on Neuronal Differentiation
por: Miranda, Cláudia C., et al.
Publicado: (2020)

All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors
por: Puppo, Francesca, et al.
Publicado: (2021)

Microscopy-based cellular contractility assay for adult, neonatal, and hiPSC cardiomyocytes
por: Scalzo, Sérgio, et al.
Publicado: (2022)

hiPSC-Derived Schwann Cells Influence Myogenic Differentiation in Neuromuscular Cocultures
por: Hörner, Sarah Janice, et al.
Publicado: (2021)

Large-scale engineering of hiPSC-derived nephron sheets and cryopreservation of their progenitors
por: Wiersma, Loes E., et al.
Publicado: (2022)

Generation of self-assembling cardiac organoids using hiPSC-derived cardiomyocytes
por: Künzel, Karolina, et al.
Publicado: (2022)

An allied reprogramming, selection, expansion and differentiation platform for creating hiPSC on microcarriers
por: Lam, Alan Tin Lun, et al.
Publicado: (2022)

Merits of hiPSC-Derived Cardiomyocytes for In Vitro Research and Testing Drug Toxicity
por: Wang, Ping-Hsien, et al.
Publicado: (2022)

Modeling Movement Disorders via Generation of hiPSC-Derived Motor Neurons
por: Akter, Masuma, et al.
Publicado: (2022)

The three-dimensionality of the hiPSC-CM spheroid contributes to the variability of the field potential
por: Hwang, Minki, et al.
Publicado: (2023)

Use of hiPSC-Derived Cardiomyocytes to Rule Out Proarrhythmic Effects of Drugs: The Case of Hydroxychloroquine in COVID-19
por: Sala, Luca, et al.
Publicado: (2022)

Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency
por: Carlessi, L, et al.
Publicado: (2014)

An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes
por: McKeithan, Wesley L., et al.
Publicado: (2017)

Inhibition of STEP(61) ameliorates deficits in mouse and hiPSC-based schizophrenia models
por: Xu, J, et al.
Publicado: (2018)

Unprecedented Potential for Neural Drug Discovery Based on Self-Organizing hiPSC Platforms
por: Cota-Coronado, Agustín, et al.
Publicado: (2020)

Comparison of Zebrafish Larvae and hiPSC Cardiomyocytes for Predicting Drug-Induced Cardiotoxicity in Humans
por: Dyballa, Sylvia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_nmi4lm21epctcoqq7k0ve2nqc3