Oncogenic Gαq activates RhoJ through PDZ-RhoGEF

Oncogenic Gα(q) causes uveal melanoma via non-canonical signaling pathways. This constitutively active mutant GTPase is also found in cutaneous melanoma, lung adenocarcinoma, and seminoma, as well as in benign vascular tumors, such as congenital hemangiomas. We recently described that PDZ-RhoGEF (al...

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Detalles Bibliográficos
Autores principales: Cervantes-Villagrana, Rodolfo Daniel, Color-Aparicio, Víctor Manuel, Castillo-Kauil, Alejandro, García-Jiménez, Irving, Beltrán-Navarro, Yarely Mabell, Reyes-Cruz, Guadalupe, Vázquez-Prado, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647656/
https://www.ncbi.nlm.nih.gov/pubmed/37958718
http://dx.doi.org/10.3390/ijms242115734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10647656/
https://www.ncbi.nlm.nih.gov/pubmed/37958718
http://dx.doi.org/10.3390/ijms242115734

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