Development and Validation of LC-MS/MS Method for the Determination of 1-Methyl-4-Nitrosopiperazine (MNP) in Multicomponent Products with Rifampicin—Analytical Challenges and Degradation Studies

Rifampicin is an essential medicine for treating and preventing tuberculosis (TB). TB is a life-threatening infectious disease and its prevention and treatment are public health imperatives. In the time of a global crisis of nitrosamine contamination of medicinal products, patient safety and a reduc...

Descripción completa

Detalles Bibliográficos
Autores principales: Witkowska, Anna B., Wołczyńska, Aleksandra, Lis-Cieplak, Agnieszka, Stolarczyk, Elżbieta U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648194/
https://www.ncbi.nlm.nih.gov/pubmed/37959824
http://dx.doi.org/10.3390/molecules28217405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648194/
https://www.ncbi.nlm.nih.gov/pubmed/37959824
http://dx.doi.org/10.3390/molecules28217405

Ejemplares similares