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Immunocheckpoint Inhibitors in Microsatellite-Stable or Proficient Mismatch Repair Metastatic Colorectal Cancer: Are We Entering a New Era?

SIMPLE SUMMARY: The majority of metastatic colorectal cancer cases are mismatch-repair-proficient and microsatellite-stable, and unfortunately this condition is associated with an inherent resistance to Immune Checkpoint Inhibitors. However, several trials are investigating the right way to overcome...

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Detalles Bibliográficos
Autores principales: Matteucci, Laura, Bittoni, Alessandro, Gallo, Graziana, Ridolfi, Laura, Passardi, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648369/
https://www.ncbi.nlm.nih.gov/pubmed/37958363
http://dx.doi.org/10.3390/cancers15215189