Identification of a Complex Karyotype Signature with Clinical Implications in AML and MDS-EB Using Gene Expression Profiling

SIMPLE SUMMARY: Complex karyotype (CK), defined as ≥3 unrelated chromosomal abnormalities, is associated with a poor prognosis in both acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Despite their high genetic complexity, complex chromosomal abnormalities in AML and MDS may share dy...

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Detalles Bibliográficos
Autores principales: Lee, Cheonghwa, Kim, Ha Nui, Kwon, Jung Ah, Hwang, Jinha, Park, Ji-Ye, Shin, Ok Sarah, Yoon, Soo-Young, Yoon, Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648390/
https://www.ncbi.nlm.nih.gov/pubmed/37958462
http://dx.doi.org/10.3390/cancers15215289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648390/
https://www.ncbi.nlm.nih.gov/pubmed/37958462
http://dx.doi.org/10.3390/cancers15215289

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