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Two Distinct E3 Ubiquitin Ligases Have Complementary Functions in the Regulation of Delta and Serrate Signaling in Drosophila

Signaling by the Notch ligands Delta (Dl) and Serrate (Ser) regulates a wide variety of essential cell-fate decisions during animal development. Two distinct E3 ubiquitin ligases, Neuralized (Neur) and Mind bomb (Mib), have been shown to regulate Dl signaling in Drosophila melanogaster and Danio rer...

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Detalles Bibliográficos
Autores principales: Le Borgne, Roland, Remaud, Sylvie, Hamel, Sophie, Schweisguth, François
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064853/
https://www.ncbi.nlm.nih.gov/pubmed/15760269
http://dx.doi.org/10.1371/journal.pbio.0030096