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Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells

Antibodies against type II collagen (anti-CII) are arthritogenic and have a crucial role in the initiation of collagen-induced arthritis. Here, we have determined the dependence of T and B cells in collagen-antibody-induced arthritis (CAIA) during different phases of arthritis. Mice deficient for B...

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Detalles Bibliográficos
Autores principales: Nandakumar, Kutty Selva, Bäcklund, Johan, Vestberg, Mikael, Holmdahl, Rikard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064861/
https://www.ncbi.nlm.nih.gov/pubmed/15535832
http://dx.doi.org/10.1186/ar1217