ADSC secretome constrains NK cell activity by attenuating IL-2-mediated JAK-STAT and AKT signaling pathway via upregulation of CIS and DUSP4

BACKGROUND: Mesenchymal stem cells (MSCs) have immunomodulatory properties and therapeutic effects on autoimmune diseases through their secreted factors, referred to as the secretome. However, the specific key factors of the MSC secretome and their mechanisms of action in immune cells have not been...

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Detalles Bibliográficos
Autores principales: Ko, Eunhee, Yoon, Taejun, Lee, Yoojin, Kim, Jongsun, Park, Yong-Beom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648656/
https://www.ncbi.nlm.nih.gov/pubmed/37964351
http://dx.doi.org/10.1186/s13287-023-03516-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648656/
https://www.ncbi.nlm.nih.gov/pubmed/37964351
http://dx.doi.org/10.1186/s13287-023-03516-z

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