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The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin
Previously we reported that the variable heavy chain region (V(H)) of a human beta(2 )glycoprotein I-dependent monoclonal antiphospholipid antibody (IS4) was dominant in conferring the ability to bind cardiolipin (CL). In contrast, the identity of the paired variable light chain region (V(L)) determ...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064879/ https://www.ncbi.nlm.nih.gov/pubmed/15642142 http://dx.doi.org/10.1186/ar1449 |