A phase I study of the safety, tolerability, and pharmacokinetics of contezolid acefosamil after intravenous and oral administration in healthy Chinese subjects

Contezolid acefosamil (also known as MRX-4), a prodrug of contezolid, is under development for treatment of multidrug-resistant Gram-positive bacterial infections. A phase I single ascending dose (SAD) and multiple-dose placebo-controlled study was conducted to assess the safety, tolerability, and p...

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Detalles Bibliográficos
Autores principales: Yang, Haijing, Jin, Yi, Wang, Hailin, Yuan, Hong, Wang, Jingjing, Li, Size, Hu, Yingying, Yang, Huahui, Li, Xin, Liang, Hong, Wu, Jufang, Cao, Guoying, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648862/
https://www.ncbi.nlm.nih.gov/pubmed/37902402
http://dx.doi.org/10.1128/aac.00796-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648862/
https://www.ncbi.nlm.nih.gov/pubmed/37902402
http://dx.doi.org/10.1128/aac.00796-23

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