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A model of inflammatory arthritis highlights a role for oncostatin M in pro-inflammatory cytokine-induced bone destruction via RANK/RANKL

Oncostatin M is a pro-inflammatory cytokine previously shown to promote marked cartilage destruction both in vitro and in vivo when in combination with IL-1 or tumour necrosis factor alpha. However, the in vivo effects of these potent cytokine combinations on bone catabolism are unknown. Using adeno...

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Detalles Bibliográficos
Autores principales: Hui, Wang, Cawston, Tim E, Richards, Carl D, Rowan, Andrew D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064887/
https://www.ncbi.nlm.nih.gov/pubmed/15642143
http://dx.doi.org/10.1186/ar1460