Tumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene expression by chondrocyte

The failure of chondrocytes to replace the lost extracellular matrix contributes to the progression of degenerative disorders of cartilage. Inflammatory mediators present in the joint regulate the breakdown of the established matrix and the synthesis of new extracellular matrix molecules. In the pre...

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Detalles Bibliográficos
Autores principales: Klooster, Aaron R, Bernier, Suzanne M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064891/
https://www.ncbi.nlm.nih.gov/pubmed/15642133
http://dx.doi.org/10.1186/ar1464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064891/
https://www.ncbi.nlm.nih.gov/pubmed/15642133
http://dx.doi.org/10.1186/ar1464

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