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Repaglinide Induces ATF6 Processing and Neuroprotection in Transgenic SOD1G93A Mice

The interaction of the activating transcription factor 6 (ATF6), a key effector of the unfolded protein response (UPR) in the endoplasmic reticulum, with the neuronal calcium sensor Downstream Regulatory Element Antagonist Modulator (DREAM) is a potential therapeutic target in neurodegeneration. Mod...

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Detalles Bibliográficos
Autores principales: Gonzalo-Gobernado, Rafael, Moreno-Martínez, Laura, González, Paz, Dopazo, Xose Manuel, Calvo, Ana Cristina, Pidal-Ladrón de Guevara, Isabel, Seisdedos, Elisa, Díaz-Muñoz, Rodrigo, Mellström, Britt, Osta, Rosario, Naranjo, José Ramón
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10648964/
https://www.ncbi.nlm.nih.gov/pubmed/37958767
http://dx.doi.org/10.3390/ijms242115783