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Enhanced Sensitivity to ALDH1A3-Dependent Ferroptosis in TMZ-Resistant Glioblastoma Cells

Temozolomide (TMZ) is standard treatment for glioblastoma (GBM); nonetheless, resistance and tumor recurrence are still major problems. In addition to its association with recurrent GBM and TMZ resistance, ALDH1A3 has a role in autophagy-dependent ferroptosis activation. In this study, we treated TM...

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Detalles Bibliográficos
Autores principales: Wu, Yang, Franzmeier, Sophie, Liesche-Starnecker, Friederike, Schlegel, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649134/
https://www.ncbi.nlm.nih.gov/pubmed/37947601
http://dx.doi.org/10.3390/cells12212522