Mechanisms of NMDA Receptor Inhibition by Sepimostat—Comparison with Nafamostat and Diarylamidine Compounds

N-methyl-D-aspartate (NMDA) receptors are inhibited by many amidine and guanidine compounds. In this work, we studied the mechanisms of their inhibition by sepimostat—an amidine-containing serine protease inhibitor with neuroprotective properties. Sepimostat inhibited native NMDA receptors in rat hi...

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Detalles Bibliográficos
Autores principales: Zhigulin, Arseniy S., Barygin, Oleg I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649274/
https://www.ncbi.nlm.nih.gov/pubmed/37958669
http://dx.doi.org/10.3390/ijms242115685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649274/
https://www.ncbi.nlm.nih.gov/pubmed/37958669
http://dx.doi.org/10.3390/ijms242115685

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