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Synaptotagmin 1 Suppresses Colorectal Cancer Metastasis by Inhibiting ERK/MAPK Signaling-Mediated Tumor Cell Pseudopodial Formation and Migration

SIMPLE SUMMARY: Colorectal cancer (CRC) is one major cause of cancer mortality worldwide. Emerging evidence shows that synaptotagmin 1 (SYT1) takes roles in a variety of cancers. However, the role of SYT1 in colorectal cancer remains an enigma. Here, we first assess SYT1 expression levels and discov...

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Detalles Bibliográficos
Autores principales: Shi, Jianyun, Li, Wenjing, Jia, Zhenhua, Peng, Ying, Hou, Jiayi, Li, Ning, Meng, Ruijuan, Fu, Wei, Feng, Yanlin, Wu, Lifei, Zhou, Lan, Wang, Deping, Shen, Jing, Chang, Jiasong, Wang, Yanqiang, Cao, Jimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649299/
https://www.ncbi.nlm.nih.gov/pubmed/37958455
http://dx.doi.org/10.3390/cancers15215282