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Heptanoate Improves Compensatory Mechanism of Glucose Homeostasis in Mitochondrial Long-Chain Fatty Acid Oxidation Defect

Defects in mitochondrial fatty acid β-oxidation (FAO) impair metabolic flexibility, which is an essential process for energy homeostasis. Very-long-chain acyl-CoA dehydrogenase (VLCADD; OMIM 609575) deficiency is the most common long-chain mitochondrial FAO disorder presenting with hypoglycemia as a...

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Detalles Bibliográficos
Autores principales: Nurjanah, Siti, Gerding, Albert, Vieira-Lara, Marcel A., Evers, Bernard, Langelaar-Makkinje, Miriam, Spiekerkoetter, Ute, Bakker, Barbara M., Tucci, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649308/
https://www.ncbi.nlm.nih.gov/pubmed/37960342
http://dx.doi.org/10.3390/nu15214689