Heat Shock Factor 1 Inhibition: A Novel Anti-Cancer Strategy with Promise for Precision Oncology

SIMPLE SUMMARY: Heat shock factor 1 (HSF1) is a transcription factor crucial for cellular stress responses. HSF1 activates heat shock proteins (HSPs) in response to proteotoxic stress, aiding in protein folding and maintaining proteostasis. HSF1 is often overexpressed in various cancer cells, fuelin...

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Detalles Bibliográficos
Autores principales: Gumilar, Khanisyah Erza, Chin, Yeh, Ibrahim, Ibrahim Haruna, Tjokroprawiro, Brahmana A., Yang, Jer-Yen, Zhou, Ming, Gassman, Natalie R., Tan, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649344/
https://www.ncbi.nlm.nih.gov/pubmed/37958341
http://dx.doi.org/10.3390/cancers15215167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649344/
https://www.ncbi.nlm.nih.gov/pubmed/37958341
http://dx.doi.org/10.3390/cancers15215167

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