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Heat Shock Factor 1 Inhibition: A Novel Anti-Cancer Strategy with Promise for Precision Oncology
SIMPLE SUMMARY: Heat shock factor 1 (HSF1) is a transcription factor crucial for cellular stress responses. HSF1 activates heat shock proteins (HSPs) in response to proteotoxic stress, aiding in protein folding and maintaining proteostasis. HSF1 is often overexpressed in various cancer cells, fuelin...
Autores principales: | Gumilar, Khanisyah Erza, Chin, Yeh, Ibrahim, Ibrahim Haruna, Tjokroprawiro, Brahmana A., Yang, Jer-Yen, Zhou, Ming, Gassman, Natalie R., Tan, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649344/ https://www.ncbi.nlm.nih.gov/pubmed/37958341 http://dx.doi.org/10.3390/cancers15215167 |
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