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Monoterpene Thiols: Synthesis and Modifications for Obtaining Biologically Active Substances
Monoterpene thiols are one of the classes of natural flavors that impart the smell of citrus fruits, grape must and wine, black currants, and guava and are used as flavoring agents in the food and perfume industries. Synthetic monoterpene thiols have found an application in asymmetric synthesis as c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649346/ https://www.ncbi.nlm.nih.gov/pubmed/37958865 http://dx.doi.org/10.3390/ijms242115884 |
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author | Sudarikov, Denis V. Nikitina, Liliya E. Rollin, Patrick Izmest’ev, Evgeniy S. Rubtsova, Svetlana A. |
author_facet | Sudarikov, Denis V. Nikitina, Liliya E. Rollin, Patrick Izmest’ev, Evgeniy S. Rubtsova, Svetlana A. |
author_sort | Sudarikov, Denis V. |
collection | PubMed |
description | Monoterpene thiols are one of the classes of natural flavors that impart the smell of citrus fruits, grape must and wine, black currants, and guava and are used as flavoring agents in the food and perfume industries. Synthetic monoterpene thiols have found an application in asymmetric synthesis as chiral auxiliaries, derivatizing agents, and ligands for metal complex catalysis and organocatalysts. Since monoterpenes and monoterpenoids are a renewable source, there are emerging trends to use monoterpene thiols as monomers for producing new types of green polymers. Monoterpene thioderivatives are also known to possess antioxidant, anticoagulant, antifungal, and antibacterial activity. The current review covers methods for the synthesis of acyclic, mono-, and bicyclic monoterpene thiols, as well as some investigations related to their usage for the preparation of the compounds with antimicrobial properties. |
format | Online Article Text |
id | pubmed-10649346 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106493462023-11-01 Monoterpene Thiols: Synthesis and Modifications for Obtaining Biologically Active Substances Sudarikov, Denis V. Nikitina, Liliya E. Rollin, Patrick Izmest’ev, Evgeniy S. Rubtsova, Svetlana A. Int J Mol Sci Review Monoterpene thiols are one of the classes of natural flavors that impart the smell of citrus fruits, grape must and wine, black currants, and guava and are used as flavoring agents in the food and perfume industries. Synthetic monoterpene thiols have found an application in asymmetric synthesis as chiral auxiliaries, derivatizing agents, and ligands for metal complex catalysis and organocatalysts. Since monoterpenes and monoterpenoids are a renewable source, there are emerging trends to use monoterpene thiols as monomers for producing new types of green polymers. Monoterpene thioderivatives are also known to possess antioxidant, anticoagulant, antifungal, and antibacterial activity. The current review covers methods for the synthesis of acyclic, mono-, and bicyclic monoterpene thiols, as well as some investigations related to their usage for the preparation of the compounds with antimicrobial properties. MDPI 2023-11-01 /pmc/articles/PMC10649346/ /pubmed/37958865 http://dx.doi.org/10.3390/ijms242115884 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sudarikov, Denis V. Nikitina, Liliya E. Rollin, Patrick Izmest’ev, Evgeniy S. Rubtsova, Svetlana A. Monoterpene Thiols: Synthesis and Modifications for Obtaining Biologically Active Substances |
title | Monoterpene Thiols: Synthesis and Modifications for Obtaining Biologically Active Substances |
title_full | Monoterpene Thiols: Synthesis and Modifications for Obtaining Biologically Active Substances |
title_fullStr | Monoterpene Thiols: Synthesis and Modifications for Obtaining Biologically Active Substances |
title_full_unstemmed | Monoterpene Thiols: Synthesis and Modifications for Obtaining Biologically Active Substances |
title_short | Monoterpene Thiols: Synthesis and Modifications for Obtaining Biologically Active Substances |
title_sort | monoterpene thiols: synthesis and modifications for obtaining biologically active substances |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649346/ https://www.ncbi.nlm.nih.gov/pubmed/37958865 http://dx.doi.org/10.3390/ijms242115884 |
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