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Pioglitazone Protects Tubular Epithelial Cells during Kidney Fibrosis by Attenuating miRNA Dysregulation and Autophagy Dysfunction Induced by TGF-β

Excessive renal TGF-β production and pro-fibrotic miRNAs are important drivers of kidney fibrosis that lack any efficient treatment. Dysfunctional autophagy might play an important role in the pathogenesis. We aimed to study the yet unknown effects of peroxisome proliferator-activated receptor-γ (PP...

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Detalles Bibliográficos
Autores principales: Manzéger, Anna, Garmaa, Gantsetseg, Mózes, Miklós M., Hansmann, Georg, Kökény, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649561/
https://www.ncbi.nlm.nih.gov/pubmed/37958504
http://dx.doi.org/10.3390/ijms242115520