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The Role of Pharmacogenetics in the Therapeutic Response to Thiopurines in the Treatment of Inflammatory Bowel Disease: A Systematic Review

This study focuses on the use of thiopurines for treating inflammatory bowel diseases (IBD). These drugs undergo enzymatic changes within the body, resulting in active and inactive metabolites that influence their therapeutic effects. The research examines the role of genetic polymorphisms in the en...

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Detalles Bibliográficos
Autores principales: Ribeiro, Aline C., Gerheim, Pâmela S. A. S., Chebli, Julio Maria Fonseca, Nascimento, Jorge Willian L., de Faria Pinto, Priscila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649589/
https://www.ncbi.nlm.nih.gov/pubmed/37959208
http://dx.doi.org/10.3390/jcm12216742