REV7 Monomer Is Unable to Participate in Double Strand Break Repair and Translesion Synthesis but Suppresses Mitotic Errors

Rev7 is a regulatory protein with roles in translesion synthesis (TLS), double strand break (DSB) repair, replication fork protection, and cell cycle regulation. Rev7 forms a homodimer in vitro using its HORMA (Hop, Rev7, Mad2) domain; however, the functional importance of Rev7 dimerization has been...

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Detalles Bibliográficos
Autores principales: Vassel, Faye M., Laverty, Daniel J., Bian, Ke, Piett, Cortt G., Hemann, Michael T., Walker, Graham C., Nagel, Zachary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649693/
https://www.ncbi.nlm.nih.gov/pubmed/37958783
http://dx.doi.org/10.3390/ijms242115799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649693/
https://www.ncbi.nlm.nih.gov/pubmed/37958783
http://dx.doi.org/10.3390/ijms242115799

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