Tuning the Envelope Structure of Enzyme Nanoreactors for In Vivo Detoxification of Organophosphates

Encapsulated phosphotriesterase nanoreactors show their efficacy in the prophylaxis and post-exposure treatment of poisoning by paraoxon. A new enzyme nanoreactor (E-nRs) containing an evolved multiple mutant (L72C/Y97F/Y99F/W263V/I280T) of Saccharolobus solfataricus phosphotriesterase (PTE) for in...

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Detalles Bibliográficos
Autores principales: Pashirova, Tatiana, Shaihutdinova, Zukhra, Tatarinov, Dmitry, Mansurova, Milana, Kazakova, Renata, Bogdanov, Andrei, Chabrière, Eric, Jacquet, Pauline, Daudé, David, Akhunzianov, Almaz A., Miftakhova, Regina R., Masson, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649860/
https://www.ncbi.nlm.nih.gov/pubmed/37958742
http://dx.doi.org/10.3390/ijms242115756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649860/
https://www.ncbi.nlm.nih.gov/pubmed/37958742
http://dx.doi.org/10.3390/ijms242115756

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