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Pharmacodynamic effects of filgotinib treatment driving clinical improvement in patients with active psoriatic arthritis enrolled in the EQUATOR trial

OBJECTIVES: The goal of this study was to identify protein and transcriptional biomarkers and pathways associated with baseline disease state, the effect of filgotinib (FIL) treatment on these biomarkers, and to investigate the mechanism of action of FIL on clinical improvement in patients with acti...

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Detalles Bibliográficos
Autores principales: Chandran, Vinod, Malkov, Vladislav A, Ito, Kaori L, Liu, Yihua, Vestergaard, Lene, Yoon, Oh Kyu, Liu, Jinfeng, Trivedi, Mona, Hertz, Angie, Gladman, Dafna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649911/
https://www.ncbi.nlm.nih.gov/pubmed/37945284
http://dx.doi.org/10.1136/rmdopen-2023-003550