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Pharmacodynamic effects of filgotinib treatment driving clinical improvement in patients with active psoriatic arthritis enrolled in the EQUATOR trial
OBJECTIVES: The goal of this study was to identify protein and transcriptional biomarkers and pathways associated with baseline disease state, the effect of filgotinib (FIL) treatment on these biomarkers, and to investigate the mechanism of action of FIL on clinical improvement in patients with acti...
Autores principales: | Chandran, Vinod, Malkov, Vladislav A, Ito, Kaori L, Liu, Yihua, Vestergaard, Lene, Yoon, Oh Kyu, Liu, Jinfeng, Trivedi, Mona, Hertz, Angie, Gladman, Dafna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10649911/ https://www.ncbi.nlm.nih.gov/pubmed/37945284 http://dx.doi.org/10.1136/rmdopen-2023-003550 |
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